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Washington University
School of Medicine
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EachOneTeachOne: St. Louis' HIV Risk
Reduction Study (EOTO)
Abstract
With 16 Cooperative Agreement sites presently
funded, America’s Midwest remains underserved in HIV prevention efforts
even though the CDC data indicate significant rates of HIV/AIDS in Midwest
cities. St. Louis, a metropolitan area with 15.3 AIDS cases per 100,000
and high rates of HIV risk behaviors, lacks intervention services which
makes it fertile ground for an intervention study. Building upon
established city-wide collaborations, the investigators propose
surveillance of the spread of HIV among out-of-treatment drug users and
the implementation and evaluation of a peer-oriented program aimed at
reducing HIV risk. The proposed new study, called EachOneTeachOne, follows
the guidelines of the NIDA Cooperative Agreement.
The Epidemiological Aims include assessing among out-of-treatment IDU and
crack cocaine users recruited from two target areas: a) HIV seroprevalence;
b) prevalence of HIV risk behaviors; c) prevalence of tuberculosis,
hepatitis B and syphilis which have similar risk factors as HIV and are
markers for the spread of HIV; d) stages of change; e) characteristics of
peer networks, and f) symptoms of depression and antisocial personality
disorder.
The Evaluation Aims involve testing the efficacy of an enhanced
peer-oriented intervention compared to a standard intervention for
reducing HIV risk behaviors at a six month follow-up. Analyses will
include: 1) a contrast of the enhanced intervention to the standard on
reduction of HIV high-risk behaviors, peer network characteristics and
stages of change, controlling for race and gender, and b) the association
of depression and antisocial personality with these behaviors.
To accomplish these aims the investigators will: 1) define two areas of
St. Louis which are at highest risk for IDU and AIDS as evidenced by DUF,
DAWN, police arrest data, and public health reports of the prevalence of
hepatitis B, syphilis, tuberculosis, HIV infection and AIDS; b) recruit 50
out-of-treatment IDU and crack cocaine users per month for 24 months
through street outreach orchestrated from two St. Louis City Health
Department satellite health centers, known as HealthStreet, which will be
located at the centers of the two areas; c) provide a standard HIV risk
reduction intervention to 35 eligible subjects per month out of the 50
recruited; d) provide the enhanced intervention, in addition to the
standard, to a minimum of 21 subjects per month randomly selected from the
35 recruited subjects; the enhanced program which has been designed to
consist of a 4-week series called " Structured Chemical Free Experiences",
will be cofacilitated by drug treatment program graduates and community
professionals, and e) conduct a six-month follow-up assessment similar to
the baseline on at least 85% of the randomized subjects. Outcome measures
will include changes in HIV risk behaviors, alcohol and drug use and
problems from drug use, incidence of HIV, stages of change, peer network
characteristics, and symptoms of depression and antisocial personality
disorder.
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Projects
National Monitoring of Adolescent Prescription Stimulants Study (N-MAPSS)
Prescription Drug Misuse,
Abuse and Dependence
Club Drug Use, Abuse, and Dependence
International Supplement
STD Supplement
Women
Teaching Women - (WTW)
Improving Treatment Services for Substance Abusers with Comorbid Depression
(SAD)
Sister
to Sister - (STS)
Nosology
Over-the-Counter Syringe Purchase in Four Communities
Analyses to Improve Reduction in Crack Use
Each
One Teach One - (EOTO)
Substance Abuse and Risk for AIDS - (SARA)
St.
Louis' Effort to Reduce the Spread of AIDS and IVDUs - (ERSA)
Community Based HIV Prevention Among Females at Risk in Bangalore INDIA
Deconstructing HIV Interventions Among Female Offenders
Enrolling and Retaining Female Offenders in HIV Trials
Collaborative MDMA and Other Club Drugs Study
Evaluating the Social Structure of a Local Heroin Market (NIDA-funded)
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