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Washington University
School of Medicine
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Risk Factors for HIV Infection in Drug Users
and Partners (SARA)
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Project Title |
Risk Factors
for HIV Infection in Drug Users and Partners (SARA) |
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Funding Source |
NIH, NIDA |
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Project Dates |
1989 - 1994 |
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Project Number |
R01-DA05585 |
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Team |
Principal Investigators-
Linda B. Cottler, Ph.D.
Co-Investigator-
Wilson Compton, M.D.
Ed Spitznagel, Ph.D.
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Abstract
The purpose of this grant application is to
continue the study of "Risk Factors of HIV Infection in Drug Users and
Partners" — DA05619. The original study, also known as the SARA study
(Substance Abuse and Risk for AIDS), was the first and only study in St.
Louis to: (1) study the prevalence of HIV infection among substance users
in an area with relatively low prevalence of reported AIDS cases but with
high prevalence of risk-related drug use behaviors and (2) evaluated the
co-occurrence of behavioral and psychiatric factors, high risk drug use
and sexual activity to better target public education efforts aimed at
reducing HIV risk behaviors. The inclusion of African Americans and
females is especially noteworthy. This project is also timely, given the
early stage of HIV infection in St. Louis and rates of high risk behaviors
and Hepatitis B which are comparable to those in cities with high rates of
HIV infection.
We propose to:
1. Analyze Wave 1 and Wave 2 SARA data to evaluate the co-occurrence of
the following among index and partner subjects: a) DSM-III and III-R
substance abuse and dependence disorders; b) presence and severity of
DSM-III-R past and current psychiatric symptoms; c) IV drug use and needle
sharing; d) risk-taking personality traits; e) high risk sexual behaviors;
f) social network characteristics; g) patterns of medical illness and
health care utilization; h) knowledge of HIV transmission; i)
sociodemographic factors and j) changes in these factors over time. 2.
Immediately begin the originally-approved reinterview of index subjects
and their sexual partners to determine the cumulative incidence rate of
HIV infection and changes in risk behaviors. 3. Educate persons in the
study on ways to change or reduce their high risk behaviors. 4. Offer HIV
positive subjects from this study the opportunity to participate in the
Washington University AIDS Clinical Trial.
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Projects
National Monitoring of Adolescent Prescription Stimulants Study (N-MAPSS)
Prescription Drug Misuse,
Abuse and Dependence
Club Drug Use, Abuse, and Dependence
International Supplement
STD Supplement
Women
Teaching Women - (WTW)
Improving Treatment Services for Substance Abusers with Comorbid Depression
(SAD)
Sister
to Sister - (STS)
Nosology
Over-the-Counter Syringe Purchase in Four Communities
Analyses to Improve Reduction in Crack Use
Each
One Teach One - (EOTO)
Substance Abuse and Risk for AIDS - (SARA)
St.
Louis' Effort to Reduce the Spread of AIDS and IVDUs - (ERSA)
Community Based HIV Prevention Among Females at Risk in Bangalore INDIA
Deconstructing HIV Interventions Among Female Offenders
Enrolling and Retaining Female Offenders in HIV Trials
Collaborative MDMA and Other Club Drugs Study
Evaluating the Social Structure of a Local Heroin Market (NIDA-funded)
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Epidemiology and Prevention Research Group 
